APPLICATION OF THE MUSCLE RELAXANT, PANCURONIUM BROMIDE, TO DOGS

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The Effect of Pancuronium Bromide as a Muscle Relaxant Alone or Combination with Diazepam in Sheep

The effect of pancuronium bromide (0.025 mg/kg. B.W.) alone or combined with diazepam (1mg/Kg. I.V) were evaluated in six adult ewes. Pancuronium bromide alone exhibited a muscle relaxants effect, but without analgesia. All baseline measurements were taken before the administration the anesthetic agent and were repeated at 5,10,15,20 and 25 min. intervals after induction an aesthesia alone or c...

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Comparative potency of pipecuronium bromide and pancuronium bromide.

Cumulative dose-response curves were constructed to determine the comparative potency of pipecuronium and pancuronium. From these, the ED50 and ED95 values were calculated. These were 24.96 micrograms kg-1 and 44.96 micrograms kg-1, respectively, for pipecuronium and 30.42 micrograms kg-1 and 61.12 micrograms kg-1, respectively, for pancuronium.

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The change in calf muscle blood flow in the ischaemic limb during anaesthesia with pancuronium bromide.

Calf muscle blood flow was measured in eight patients with confirmed ischaemic disease of their lower limbs, before and during general anaesthesia which included pancuronium bromide and intermittent positive pressure ventilation. Anaesthesia was associated with a decrease in limb blood flow. Comparison of these results with those of a similar study in which tubocurarine was employed in a place ...

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Pancuronium bromide induced joint contractures in the newborn.

We report three infants paralysed with pancuronium bromide as an adjunct to mechanical ventilation, who developed multiple joint contractures. In two term infants, gentamicin and phenobarbitone given together with pancuronium may have potentiated its effect, and in one preterm infant contractures, which became more severe after paralysis, were present at birth.

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ژورنال

عنوان ژورنال: The Japanese Journal of Veterinary Anesthesiology

سال: 1979

ISSN: 0285-2209,2185-2987

DOI: 10.2327/jvas1970.10.51